PNC-27 5mg

Buy PNC-27 5mg

Introduction

PNC-27 is part of the PNC set of investigational peptides aimed at combating cancer. It works by binding to HDM-2, a protein present in cancer cell membranes, and inducing membranolysis, leading to selective cancer cell death. This peptide has shown promise in preclinical studies for its specificity in targeting cancerous cells without harming normal tissues.

Product Details

• Molecular Formula: C188H293N53O44S
• Molecular Weight: 4031.7 g/mol

Benefits and Applications

PNC-27 offers several potential research benefits:

• Selective Cancer Cell Destruction: PNC-27 has been demonstrated to selectively kill cancer cells by binding to HDM-2 in their membranes, causing cell death through membranolysis. This selectivity minimizes damage to healthy cells, making it a promising candidate for cancer research.
• Wide Cancer Targeting: Research shows that PNC-27 is effective against various cancer types, including pancreatic cancer, breast cancer, leukemia, melanoma, and other cancer lines. Its ability to target multiple cancer forms makes it a versatile tool in oncology research.
• Non-Toxic Mechanism: The peptide’s non-toxic mechanism allows it to induce cancer cell death without the severe side effects often associated with traditional cancer therapies. This characteristic could make PNC-27 a valuable adjunct or alternative in cancer treatment research.

How PNC-27 Works

PNC-27 functions by binding to HDM-2 in the membranes of cancer cells. Once attached, it creates pores in the membrane, leading to an influx of extracellular fluid, osmotic imbalance, and eventual cell death through rapid implosion. This process, called membranolysis, is highly specific to cancer cells due to their unique expression of HDM-2, ensuring minimal impact on healthy cells.

Clinical Studies

Research published in 2010 by Drs. Ehsan Sarafraz-Yazdi et al. detailed PNC-27’s mechanism of action and its potential in cancer therapy. The study highlighted the peptide’s ability to form oligomeric pores in cancer cell membranes, leading to selective cell death. The research suggested that PNC-27’s targeting of MDM2 in cancer cell membranes offers significant potential for developing new cancer treatments.

Quality Assurance

PNC-27 is synthesized under strict quality control measures to ensure high purity and consistency for research purposes. Each batch undergoes rigorous testing to validate its structural and functional integrity.

Usage Instructions

PNC-27 5mg is intended for research use only. Proper handling and storage are crucial to maintain its stability and efficacy for experimental applications.

Shipping and Handling

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Customer Support

For any inquiries about PNC-27, our expert support team is available 24/7. Contact us at service@peptidesciencehub.com for assistance.

Legal Disclaimer

PNC-27 5mg is for educational and scientific research use only. It is not intended for human consumption. Researchers must adhere to local regulations and guidelines when using this product.

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