PE-22-28

Buy PE-22-28

Introduction

PE-22-28 is a groundbreaking synthetic analog of spadin, a naturally secreted peptide derived from sortilin. It targets the TREK-1 (TWIK-related potassium channel) receptor, a two-pore potassium channel involved in regulating neuronal excitability. TREK-1 is predominantly found in brain regions critical for mood regulation, memory, and learning, such as the prefrontal cortex, amygdala, and hippocampus. Research indicates that PE-22-28 not only enhances mood by acting as an antidepressant but also promotes neurogenesis and synaptogenesis, offering potential therapeutic benefits for stroke recovery and neurodegenerative diseases.

Product Details

• Spadin Sequence: YAPLPRWSGPIGVSWGLR
• Spadin Molecular Formula: C96H142N26O22
• Spadin Molecular Weight: 2012.35 g/mol
• PE-22-28 Sequence: GVSWGLR
• PE-22-28 Molecular Formula: C35H55N11O9
• PE-22-28 Molecular Weight: 773.89 g/mol
• Primary Target: TREK-1 receptor

Benefits and Applications

PE-22-28 is under extensive investigation for several key applications:

• Antidepressant Activity: Unlike traditional antidepressants that may take weeks to show effects, PE-22-28 has demonstrated the ability to relieve depressive symptoms in just four days without notable side effects. Its mechanism of action involves inhibiting the TREK-1 channel, which has been linked to mood regulation.
• Neurogenesis and Synaptogenesis: Research shows that PE-22-28 induces the growth of new neurons and strengthens synaptic connections in the hippocampus. This rapid enhancement of neural plasticity positions PE-22-28 as a promising agent in cognitive enhancement therapies.
• Stroke Recovery: Post-stroke depression (PSD) is a common complication, often resistant to standard treatments. PE-22-28’s ability to modulate TREK-1 activity suggests it could offer new avenues for treating PSD, accelerating recovery and improving patient outcomes.
• Neurodegenerative Diseases: PE-22-28’s potential to stimulate neurogenesis and modulate neural excitability makes it a candidate for research in Alzheimer’s disease and other neurodegenerative conditions. By enhancing cognitive function and protecting neurons, PE-22-28 may slow the progression of these diseases.

Quality Assurance

PE-22-28 is synthesized under stringent quality control measures to ensure purity and consistency, meeting the high standards required for advanced research. Each batch undergoes rigorous testing to confirm its chemical composition and biological activity.

Usage Instructions

PE-22-28 is intended strictly for research use. Researchers should follow all safety protocols and guidelines when handling this peptide. Proper storage conditions are essential to maintain its stability and effectiveness.

Shipping and Handling

Orders placed before noon PST are shipped the same business day. Peptide Science Hub offers free shipping for orders over $200, and we provide tracking details to ensure timely and reliable delivery. We ship worldwide from the USA and Europe, minimizing customs delays and ensuring optimal delivery times.

Customer Support

Our dedicated support team is available 24/7 to assist with any inquiries or issues related to PE-22-28. Contact us at service@peptidesciencehub.com for expert guidance and support.

Legal Disclaimer

PE-22-28 is sold for research purposes only and is not approved for human consumption or clinical use. Researchers are responsible for ensuring compliance with local regulations and guidelines when using this product.

Call to Action

Unlock new potential in neurological research with PE-22-28. Order now to explore its groundbreaking applications in depression treatment, cognitive enhancement, and neuroprotection, with the assurance of high-quality, reliable service from Peptide Science Hub.