B7-33 6mg

Buy B7-33 6mg

Introduction
B7-33 is a single-chain peptide designed to harness the anti-fibrotic properties of the naturally occurring protein H2-relaxin. Unlike its parent protein, B7-33 selectively activates the pERK pathway without stimulating cAMP production, thereby offering targeted anti-fibrotic effects without the associated risks of tumor promotion or increased heart rate.

Product Details

• Active Ingredient: B7-33
• Concentration: 6mg per vial
• Form: Lyophilized powder for research use
• Sequence: VIKLSGRELVRAQIAISGMSTWSKRSL
• Molecular Formula: C152H242N44O46S3
• Molecular Weight: 3477.94 g/mol
• CAS Number: N/A
• Synonyms: (B7-33)H2, GTPL9321

Benefits and Applications
1. Anti-Fibrotic Effects
In animal studies, B7-33 has demonstrated remarkable efficacy in reducing fibrosis by approximately 50%, significantly improving survival rates after injury. Its potential applications extend to treating acute and chronic conditions such as heart failure, lung inflammation, and kidney disease, marking a significant advancement in fibrosis research.

2. Cardiac Health and Heart Failure
B7-33 has shown promise in reducing cardiac fibrosis, a key contributor to heart failure. By targeting the RXFP1 receptor and activating pERK1/2 signaling, the peptide enhances collagen degradation, improving heart function and reducing long-term scarring post-injury. This positions B7-33 as a pivotal tool in heart failure treatment, offering new hope after 20 years without novel therapeutic advancements.

3. Vascular Disorders and Preeclampsia
Research suggests that B7-33 has vasoprotective properties, enhancing bradykinin-mediated relaxation in arteries and supporting vascular health. This makes it a potential therapeutic option for vascular disorders and preeclampsia, improving maternal-fetal blood flow and potentially reducing complications during pregnancy.

4. Anti-Fibrotic Coatings for Medical Implants
B7-33’s ability to reduce fibrotic capsule formation around implanted devices presents a novel approach to improving the longevity and functionality of medical implants. This application could reduce the need for systemic anti-fibrotic drugs, making implants safer and more effective.

Quality Assurance
Peptide Science Hub guarantees B7-33 6mg is synthesized with over 99% purity and undergoes stringent quality control in our in-house analytical lab, ensuring reliable and reproducible research outcomes.

Usage Instructions

• Handling: Reconstitute with a suitable solution as per research protocol.
• Storage: Store in a cool, dry place. Use immediately after reconstitution or follow storage guidelines.
• Research Use Only: This product is intended for laboratory research purposes and is not for human use.

Shipping and Handling
We offer worldwide shipping with various options, including free shipping on orders over $200. Orders placed before noon PST are shipped the same business day, with tracking information provided.

Customer Support
For inquiries, contact us at service@peptidesciencehub.com. Cancellations are accepted before shipment, but returns are not due to the nature of the product.

Legal Disclaimer
B7-33 6mg is for research purposes only and not approved for human or veterinary use. The provided information is for educational purposes and should not be considered medical advice. Proper laboratory safety protocols should be observed.

Call to Action
Explore the potential of B7-33 6mg in fibrosis research and beyond. Order from Peptide Science Hub for high-quality peptides, reliable service, and comprehensive support for your research needs.